Survival-associated eQTLs across different cancer types
We identified 22,212 eQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
|
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
|---|---|---|---|---|---|---|---|---|---|
| THCA | rs75182663 | chr10:105058104 | A/G | 1.27E-5 | 478 | 15.3 | 18.18 | 10.17 | KM Plot |
| THCA | rs7518880 | chr1:41503820 | C/A | 3.73E-12 | 489 | 17.7 | 17.73 | 14.92 | KM Plot |
| THCA | rs75201916 | chr14:36227146 | A/C | 5.07E-6 | 490 | 16.08 | 15.98 | 8.33 | KM Plot |
| THCA | rs75208167 | chr2:48098652 | C/T | 4.85E-8 | 490 | 15.23 | 19.47 | 8.27 | KM Plot |
| THCA | rs75212707 | chr11:62608853 | G/A | 7.55E-5 | 490 | 16.22 | 14.33 | 14.27 | KM Plot |
| THCA | rs75219158 | chr10:104747594 | C/T | 6.25E-9 | 488 | 15.3 | 17.63 | 32.1 | KM Plot |
| THCA | rs7523558 | chr1:16346732 | G/A | 1.38E-11 | 483 | 15.17 | 19.47 | 12.63 | KM Plot |
| THCA | rs7525193 | chr1:41520712 | T/C | 3.77E-12 | 488 | 17.7 | 17.73 | 14.93 | KM Plot |
| THCA | rs75266232 | chr1:220843038 | A/G | 2.73E-5 | 483 | 15.93 | 15.23 | 0.23 | KM Plot |
| THCA | rs75266488 | chr11:62580310 | T/C | 7.62E-5 | 489 | 16.2 | 14.33 | 14.27 | KM Plot |
| THCA | rs7527606 | chr1:166966612 | C/T | 3.91E-10 | 490 | 15.67 | 15.7 | 17.27 | KM Plot |
| THCA | rs75283377 | chr6:24414026 | G/A | 4.77E-15 | 489 | 16.38 | 14.85 | 11.07 | KM Plot |
| THCA | rs75313266 | chr14:59755541 | G/A | 1.4E-8 | 488 | 16.38 | 12.62 | 5.45 | KM Plot |
| THCA | rs7531344 | chr1:41507431 | C/G | 3.75E-12 | 490 | 17.7 | 17.7 | 14.93 | KM Plot |
| THCA | rs75316086 | chr6:24464311 | TA/T | 0 | 484 | 16.6 | 14.78 | 8.88 | KM Plot |